Annual Meeting

2016 Annual Meeting

If you have a proposal or Director nomination that you would like us to include in our Proxy Statement and form of proxy for, or to present at the 2016 Annual Meeting of Stockholders, you must send the proposal to us by no later than January 19, 2016. Stockholders wishing to submit proposals or Director nominations that are not to be included in such Proxy Statement and form of proxy must do so no later than the close of business on March 2, 2016. Stockholders should also review our bylaws, which contain additional requirements with respect to advance notice of stockholder proposals and Director nominations.

2015 Annual Meeting

Isis Pharmaceuticals, Inc. held its Annual Meeting of Stockholders on June 30, 2015. The stockholders considered five proposals, each of which is described in more detail in the Company’s definitive proxy statement filed with the SEC on May 15, 2015.

Proposal 1:

Election of directors to hold office until the 2018 Annual Meeting:

FOR

WITHHELD

BROKER
NON-VOTES

Breaux B. Castleman

77,962,275

776,948

23,456,504

Frederick T. Muto

71,820,742

6,918,481

23,456,504

The Company’s stockholders elected the foregoing candidates, by affirmative votes by a majority of the votes of the shares represented in person or by proxy at the meeting and entitled to vote in the election of Directors.

Proposal 2:

Approve an amendment to the Isis Pharmaceuticals, Inc. 2011 Equity Incentive Plan.

 

FOR

AGAINST

ABSTAIN

BROKER NON-VOTES

70,922,269

7,611,423

205,531

23,456,504

The Company’s stockholders approved the foregoing proposal.

Proposal 3:

Approve an amendment to the Isis Pharmaceuticals, Inc. Amended and Restated 2002 Non-Employee Directors’ Stock Option Plan

FOR

AGAINST

ABSTAIN

BROKER NON-VOTES

66,907,012

11,615,809

216,402

23,456,504

The Company’s stockholders approved the foregoing proposal.

Proposal 4:

Approval, on an advisory basis, of the compensation paid to the Company’s executive officers, including the following resolution:

“RESOLVED, that Isis’ stockholders approve, on an advisory basis, the compensation of the named executive officers, as disclosed in this Proxy Statement for the 2015 Annual Meeting of Stockholders pursuant to the compensation disclosure rules of the Securities and Exchange Commission.”


FOR 

AGAINST

ABSTAIN

BROKER NON-VOTES

76,803,604

1,661,946

273,673

23,456,504

The Company’s stockholders approved the foregoing proposal.


Proposal 5:

Ratify the Audit Committee's selection of Ernst & Young LLP as independent auditors for our 2015 fiscal year:

FOR

AGAINST

ABSTAIN

BROKER NON-VOTES

101,160,877

503,428

543,422

0

The Company’s stockholders approved the foregoing proposal.